e drug Yondelis (Trabectedin) - Yondelis (Trabectedin) is an analogue of an anticancer drug. Original medicine. The main active ingredient is Trabekedin. Indications for use Treatment: - ovarian cancers, in patients who have already received treatment with drugs-derivatives of platinum; - metastatic soft tissue sarcomas in the absence of the effect of treatment with anthracyclines and phosphamides. Yondelis (Trabectedin) - Yondelis (Trabectedin) has the ability to block DNA transcription during the cell division cycle. Thus, it effectively suppresses the multiplication of tumor cells ..
Mode of application In the treatment of metastatic soft tissue sarcomas, the standard dosage of the drug is 1.5 mg per 1 m2 of patient's body area. In this case, the introduction of Yondelis is carried out for 24 hours with an interval of 21 days. In the treatment of ovarian cancer, the dosage of the drug is 1.1 mg per 1 m2 of the patient's body area. In this case, the infusion lasts about 3 hours, with a 21-day interval. The use of Yondelis in all groups of patients should include mandatory premedication with glucocorticosteroid drugs. There are only positive reviews about the drug Yondelis (Trabectedin) - Yondelis (Trabectedin) . Contraindications Contraindications include the following: • individual intolerance to cabozantinib or other components contained in the preparation; • tendency to form blood clots; • osteolysis of bones (complete aseptic resorption of all elements of bone tissue); • unstable hypertension; • pregnancy and breastfeeding; • the patient's age is less than 18 years.
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