One of the newest anticancer drugs for the treatment of melanoma is Tafinlar 50mg (Dabrafenib) - Tafinlar (Dabrafenib) . The medicine is used for the most aggressive form of skin cancer - metastatic. In such a situation, the patient is no longer subject to surgical treatment. The drug is produced in the UK, but it is successfully used in other countries of the world. Principle of operation and composition The drug is available in the form of pink capsules with a volume of 50 and 75 ml. The active ingredient is dabrafenib. In addition to it, a number of auxiliary components are present in the composition of the drug, such as microcrystalline cellulose, silicon dioxide and magnesium stearate. Dabrafenib is used in combination treatment with Mekinist or alone. The clinical effect is based on the effect of the active substance on the cells of the neoplasm, as a result of which the pathologically altered BRAF gene is blocked and the tumor stops growing. The drug participated in clinical trials and proved to be effective in the fight against melanoma, retaining the therapeutic effect for longer than using chemotherapy. In addition, it was found that the greatest result in reducing tumor growth was achieved when it was used together with drugs based on trametinib. Find out which one is onTafinlar 50mg (Dabrafenib) - Tafinlar (Dabrafenib) price you can contact the manager of our online pharmacy.
Indications and contraindications for use Dabrafenib is prescribed only after specialized testing of a patient with metastatic melanoma, when a BRAF gene mutation is detected. However, it has a number of contraindications that you should be aware of. These include: • Age limit. The medicine is prohibited to be taken by persons under 18 years of age. • Pregnancy and breastfeeding. It is highly toxic. • Concurrent use with nefazodone, clarithromycin, ketoconazole, gemfibrozil, phenytoin, rifamlicin, phenobarbital, carbamazeline, because this reduces its activity. Caution should be exercised when taking medication for people with abnormalities in the functioning of the liver and kidneys, as well as those suffering from diabetes. You can read about the drug Tafinlar 50mg (Dabrafenib) - Tafinlar (Dabrafenib) reviews on the forums - as a rule, they are positive. Side effects The drug can cause side effects of varying severity. In some cases, with a significant deterioration in well-being after taking the capsules, the doctor reduces the dose of the drug. It is forbidden to do this on your own. Undesirable consequences include: • Vomiting with severe coughing (sometimes with bloody discharge). • Headaches and increased fatigue. • Fluid retention and soreness in the limbs. • Dark, bloody stool. • The appearance of blood clots. • Difficulty breathing and shortness of breath. • Jumps in blood pressure, chills. • A noticeable decrease in visual activity, redness of the eyes. • Lack of iron in the blood. • Skin rashes. • Exacerbation of the disease. • The initial stage of baldness (partial hair loss). It should be borne in mind that the active substance negatively affects the reproductive system of the body of both women and men. If you are interested inTafinlar 50mg (Dabrafenib) - Tafinlar (Dabrafenib) cost - the current price can be checked with the employee of our online pharmacy.
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