Casodex (Bicalutamide) - Casodex (Bicalutamide) - the drug is a racemic mixture, antiandrogenic activity is predominantly (R) -enantiomer. The drug does not show other types of endocrine activity. Casodex (Bicalutamide) - Casodex (Bicalutamide) binds to androgen receptors and, without activating gene expression, suppresses the stimulating effect of androgens. As a result, regression of prostate neoplasms occurs. In some patients, discontinuation of Casodex may lead to the development of a clinical "antiandrogen withdrawal syndrome". For Casodex (Bicalutamide) - Casodex (Bicalutamide), the price is significantly lower than the original, which makes the medicine more affordable for patients.
Dosage and method of administration The prearate is prescribed only to adult men, including the elderly, with advanced prostate cancer in combination with a GnRH analog or with surgical castration at a dose of 50 mg 1 time / day. Treatment should be started at the same time as the initiation of a GnRH analog or surgical castration. Patients with impaired renal function and mild impaired liver function do not require dose adjustment. In patients with moderate and severe impairment of liver function, an increased cumulation of the drug may be observed. Due to the high efficiency of Casodex (Bicalutamide) - Casodex (Bicalutamide), patient reviews are mostly positive. Most patients report an improvement in their well-being.
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